Mental Health Awareness Month in South Africa

Dual Diagnosis: Addiction and Other Mental Illnesses

During mental health awareness month, we educate professionals and the public alike with a specific focus on addiction as a brain disease and how it often occurs alongside other mental health problems like major depression, ADHD and bipolar mood disorder. This phenomenon is termed dual diagnosis.

About 40% of addicts and alcoholics have a co-occurring mental illness while an estimated 20% of all people diagnosed with a mental illness suffer from a substance abuse problem, according to the National Institute on Drug Abuse.

“Dual diagnosis refers to the formal diagnosis of simultaneous mental health and substance use disorders,” explained psychologist Kate Saxton who is the practice manager at Changes Addiction Rehab in Northcliff, Johannesburg. “Either illness can develop first, but drug and alcohol use can exacerbate symptoms of mental health issues. Treating both disorders is crucial for lasting recovery,” she said.

Diagnosis and treatment for co-occurrence or dual diagnosis can be complicated because it is difficult to assess the overlapping symptoms of addiction and mental illness.

“Nevertheless, it is essential, as failure to treat both conditions places a person at a greater risk of relapse,” added Saxton.

Addiction rehab centres that offer dual-diagnosis treatment give their patients a much better chance of sustained recovery or sobriety, yet many of these facilities are not equipped to handle dual-diagnosis cases.
Apart from relapse, untreated dual diagnosis can leave a person vulnerable to other serious consequences including:

  • Aggression
  • Increase risky sexual activity
  • Low quality of self-care
  • Physical health problems
  • Suicide
Mental Health Awareness Month

Chicken and the Egg: Which Comes First?

In many instances, people resort to alcohol and/or drug use and abuse to cope with symptoms of mental illness.

“For instance, someone struggling with depression turns to illicit drug use to suppress their emotional turmoil. Another person with anxiety may try an opiate as a sedative, and they may quickly develop a dependence on the drug,” explained Saxton. But the opposite of this is also true. “An individual may develop mental health problems as a result of substance use. Since drugs alter brain chemistry and function, a person could begin struggling with depression or other mental health illnesses, due to the use of substances,” she said.

Drug and alcohol abuse may also trigger an underlying mental health issue.

How to Treat Dual Diagnosis

Dual diagnosis can be difficult but there are a couple of clear indicators for treatment, according to Saxton.

  1. Detox needs to ensure that the mind-altering substance is safely removed from the system as a priority.
  2. Following detox, the individual will start the addiction rehab process.
  3. But at the same time, they should be seen by a specialist psychiatrist and given the correct medication to ensure that the client is stabilised.
  4. Should a client be psychotic, they would need to be stabilised before the addiction rehab process can truly be effective.
  5. Hence, a specialist psychiatrist, who works within a multi-disciplinary team, is the best option for a dual-diagnosis patient.

“Training and services for mental health and substance misuse generally don’t overlap, so professionals in one field aren’t always knowledgeable about the issues in the other field. It can be hard to find professionals who are skilled in treating both substance misuse and mental illness,” explained Saxton.

Importantly, people who experience dual diagnosis issues (addiction and mental health problems) are affected in different ways and therefore have individual needs. In practice, what is effective for one person may not be effective for another. “A dual diagnosis comes with a whole set of unique issues, and understanding these issues is key to addiction rehab treatment and recovery.”

Board Of Healthcare Funders in South Africa
Hospital Association Of South Africa
Department of Social Development in South Africa
Department of Health South Africa
National Hospital Network South Africa

Mental Health Awareness Month in SA

Up to 50% of people with ADHD have a substance abuse problem. ADHD is the most common psychiatric disorder in children and symptoms persist into adulthood in 30 – 80% of cases. ADHD is characterised by inattention, hyperactivity and impulsive behaviour.

People with ADHD have been found to start abusing substances at a younger age when compared to addicts and alcoholics without ADHD.

Addiction tends to make ADHD symptoms worse and vice versa. However, research shows that treating ADHD alongside addiction treatment improves outcomes and reduces the rates of relapse. Read more about the link between ADHD and addiction here.

Some research suggests that up to 60% of people with bipolar disorder have some kind of history of substance abuse. Studies have also estimated that people with bipolar 1 are three times more likely to abuse or be dependent on alcohol and seven times more likely to abuse or be dependent on drugs when compared to the general population.

Bipolar is a mood disorder characterised by manic and depressive episodes that significantly impact a person’s ability to function healthily. Substance use can make bipolar symptoms worse as well as trigger the onset of dormant bipolar. Untreated bipolar can significantly impact a person’s ability to stay clean and sober by increasing the chances of relapse. Both conditions need to be treated simultaneously.

Read more about the link between addiction and bipolar mood disorder here.

Everyone experiences some level of anxiety but you may be diagnosed with an anxiety disorder if your symptoms are extreme and interfere with your daily functioning.

Some research suggests about 30% of people with an addiction have also had an anxiety disorder at some point in their lifetime. About 20% of people with an anxiety disorder have experienced a substance abuse problem in their lifetime.

Drugs and alcohol may offer people suffering from anxiety relief in the short term but substance abuse invariably leads to anxiety symptoms worsening in the long-term.

Untreated anxiety increases the likelihood of relapse as well as poor outcomes of addiction treatment. An experienced psychiatrist will be able to differentiate an anxiety disorder from withdrawal-related anxiety in the treatment environment as well as treat both conditions accordingly.

Read more about the link between addiction and anxiety here.

Trauma and addiction have a strong link. Some research on adolescents in the United States estimates that up to 70% of people being treated for substance use disorders have a history of trauma.

PTSD (post-traumatic stress disorder) is an illness that develops in some people after they experience a particularly traumatic event. According to a 2010 study, almost 60% of young people with PTSD go on to develop substance abuse problems.

South Africa has comparatively high rates of trauma and PTSD which is a significant driver of the country’s addiction epidemic. A nationally representative survey found that 75% of South Africans had experienced a traumatic event and about half had experienced more than one trauma.

It is thought that people turn to substances to self-medicate symptoms of PTSD. Such individuals may need to use more and more of the substance to experience temporary relief: This cycle often leads to the development of an addiction. Although substance use helps people with PTSD in the short term, abusing substances usually ends up making PTSD symptoms worse in the long term. Both need to be treated simultaneously for the best chance at recovery.

Read more about the link between addiction and PTSD here.

What’s the Link Between PTSD and Addiction?

Brian Muhumuza is a Addictions Counsellor at Changes Rehab in JHB

Brian MuhumuzaRead Bio

Addictions Counsellor

Dedicated to addiction recovery.

Clients Questions

Why are bipolar disorder, depression and ADHD so often missed when a South African presents with substance dependence?

Because substance use masks and mimics psychiatric symptoms and our systems encourage that mistake. Intoxication, withdrawal and drug-induced mood swings look like primary depression or mania; overstretched clinics triage the obvious addiction and never get the collateral history or suspension of substances needed for a clean diagnostic picture. Clinically you need timelines (when did mood symptoms start versus when did substance use escalate), input from family or schools, and repeated assessments after periods of stabilization. In practice in Johannesburg many people never get that follow-up assessment: they leave detox and are treated only for the addiction. The result is diagnostic overshadowing — a treatable bipolar or ADHD remains untreated, increasing relapse risk, self-medication and crises. Insist on documented reassessment windows, objective screening tools, and collateral history before accepting a one-line diagnosis of ‘substance-induced’ everything.

Can we safely treat ADHD with stimulants if the person is still using drugs or alcohol?

Yes — but only with clear safeguards. Stimulants are not an automatic no-go simply because there’s substance use; what matters is pattern, risk of diversion and the formulation. Long‑acting prodrugs (lisdexamfetamine) or extended-release methylphenidate reduce misuse risk compared with immediate-release tablets, and non‑stimulant options (atomoxetine, bupropion) exist. In South Africa you need to pair any prescription with urine drug screening, observed dispensing or family supervision, a written monitoring plan and frequent reviews by a clinician experienced in dual diagnosis. If there’s active opioid or benzodiazepine misuse, stabilise and address that first where possible; but withholding ADHD treatment indefinitely because of past use often worsens outcomes and drives people deeper into self-medication. This is clinical risk management, not moral judgement.

How do public‑sector realities in Johannesburg affect integrated care for bipolar disorder and addiction?

Reality: psychiatry posts are scarce, beds are limited, and addiction services aren’t routinely co‑located with mental health or HIV/TB clinics. That means fragmented care — a patient gets methadone in one place, antipsychotics in another, and nobody looks at drug‑drug interactions or a coherent follow‑up plan. Workarounds that actually help: task‑sharing (trained primary care clinicians managing stable bipolar on a shared protocol), rapid telepsychiatry consults, and linkage with community programmes (for example COSUP where available) for harm reduction and opioid substitution. Families and clinicians must proactively coordinate: get written referrals, medication lists, baseline ECGs and liver tests, and set up a single clinician or clinic responsible for medication reconciliation. Without that, people fall through the cracks and end up in emergency services.

What specific things should a family demand from a rehab or clinic to know coexisting depression or bipolar disorder will be treated properly?

Ask for a psychiatrist or psychiatric nurse practitioner assessment documented in writing; a clear differential diagnosis that explains how substance effects were separated from primary mood disorder; a medication plan including indications, expected side effects, monitoring schedule (ECG if on QT‑prolonging drugs or methadone; LFTs for valproate; lithium levels if used); routine urine drug screens and how results change management; integration plans with HIV/TB care if applicable; a crisis and relapse plan; and explicit aftercare/step‑down arrangements with public clinics or NGOs if you can’t afford private follow‑up. If any of those are missing, the facility is offering symptom control at best, not integrated dual‑diagnosis care. Don’t accept vague promises — get it on paper.

How do HIV, TB and opioid substitution programmes in South Africa change choices and monitoring for psychiatric medications?

They change everything. Rifampicin (used in TB) accelerates metabolism of many psychotropics and drastically reduces methadone levels — causing withdrawal or reduced methadone effectiveness. Some ARVs (efavirenz historically) can worsen mood or psychosis and interact with antidepressants and antipsychotics. Methadone itself prolongs QT and interacts with several antipsychotics; buprenorphine has fewer severe interactions and is often the safer opioid‑substitution option where available. In practice you must coordinate with the patient’s ART/TB program before starting mood stabilisers: check drug interaction charts, do baseline ECG and LFTs, and plan for closer therapeutic drug monitoring (lithium/valproate) and more frequent clinic reviews. Integrated care isn’t a nice extra here — it’s mandatory clinical safety in South Africa’s overlapping epidemics.

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Content on this website is for general information only and is not a substitute for professional medical advice, diagnosis, or treatment. Always speak to a qualified health professional about any medical concerns.
Changes Addiction Rehab PTY LTD (‎2013/152102/07) is licensed by the South African Department of Social Development (Practice No. 0470000537861) and the Department of Health, and is a registered detox facility and practice with the Board of Healthcare Funders. Our treatment programme is led by counsellors registered with the HPCSA, working alongside a multidisciplinary team of medical professionals under a unified practice. We are proud, standing members of the International Certification & Reciprocity Consortium (IC&RC), the Occupational Therapy Association of South Africa, the South African Council for Social Service Professions, the South African Medical Association, the South African Nursing Council and the South African Society of Psychiatrists. Changes Addiction Rehab has been in continuous professional operation since 2007, when it was founded by Sheryl Rahme, who has worked in the addiction treatment field since 1984. Our core clinical team brings over 100 years of combined professional addiction recovery experience.